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GLP-1 and GLP-2 medications effects on facial appearance and skin volume
Home » Cosmetic Dermatology » GLP-1 & GLP-2 Medications & Your Face: What You Need to Know

GLP-1 & GLP-2 Medications & Your Face: What You Need to Know


Weight loss drugs are highly effective, but there is a hidden cost: rapid fat loss affects more than just the number on the scale. It also impacts your skin, facial volume, and collagen support. Board-certified cosmetic dermatologist Dr. Hellman developed treatment plans to prevent and address skin conditions in patients on GLP medications, including GLP-1 and GLP-2 therapies such as Ozempic and Zepbound.

Many patients experience:

  • Sagging skin on the face, neck, and jawline
  • A hollowed or gaunt appearance, often referred to as “GLP-related facial volume loss” (sometimes called “Ozempic
    face”)
  • Loss of firmness in the arms, abdomen, and thighs
  • Crepey skin that does not tighten on its own

These changes occur because fat loss happens faster than the skin can contract, while natural collagen production continues to decline with age.

The key is timing — these effects can be prevented when addressed early, or effectively treated once they appear.

InMode Boost

Skin Tightening and Fat Reduction

Ideal for patients who are early in their GLP medication treatment or who want to prevent skin laxity before it develops.

Benefits:

  • Improves skin firmness and elasticity
  • Helps prevent sagging during rapid weight loss
  • Targets small, stubborn fat pockets
  • Encourages collagen production as weight decreases

Treatments Included:

  • Forma – radiofrequency skin tightening to stimulate collagen and elastin
  • MiniFX – vacuum-assisted radiofrequency to reduce fat cells while tightening skin

Common treatment areas include the face, jawline, neck, arms, abdomen, and thighs.

There is minimal to no downtime, making it ideal for ongoing maintenance.

InMode Lift

Advanced Tightening, Rejuvenation, and Lift

Designed for patients who want to proactively support skin firmness and facial structure during weight loss, or who are concerned about early changes before laxity becomes pronounced.

Benefits:

  • Tightens and supports skin before laxity becomes pronounced
  • Improves facial contours and definition
  • Enhances skin texture and firmness
  • Stimulates deep collagen remodeling

Treatments Included:

  • Forma – surface-level skin tightening
  • MiniFX – fat reduction with skin contraction
  • Morpheus8 – radiofrequency microneedling to remodel deeper layers of skin

This plan is ideal for the face, neck, jawline, and body areas requiring more noticeable support and tightening.

Prevent or Restore Skin Laxity With InMode Technology

At Hellman Dermatology, we focus on proactive and corrective skin tightening using advanced InMode echnology to support your skin throughout your weight loss journey.

We offer two customized treatment plans, depending on whether your goal is prevention or correction.

Weight Loss Should Not Mean Looking Older

GLP medications, including GLP-1 and GLP-2 therapies such as Ozempic and Zepbound, can significantly improve health and confidence. Your skin should reflect those results, not detract from them.

Whether your goal is to prevent GLP-related skin changes or restore firmness and lift during or after weight loss, Hellman Dermatology creates personalized treatment plans that work alongside your transformation.

Schedule Your Consultation

Protect your results and maintain a natural, refreshed appearance.

Schedule a consultation at Hellman Dermatology to determine the best treatment plan for your needs.

Schedule Your Consultation

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At our office, Only Board-Certified Dermatologists See Patients & Perform Treatments

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Judith Hellman

About the Author

Dr. Judith Hellman is a board-certified dermatologist and an associate professor at Mt. Sinai Medical Center. Her passion for people shines through when consulting on a diverse range of medical skin conditions and how these may affect health, aesthetics, and self-esteem. Dr. Hellman has lectured globally and has authored many journal articles. Her fluency in English, Hungarian, and Hebrew helps enhance multilingual communication for many dermatology patients in NYC.

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